Application of 213265-83-9, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 213265-83-9, name is 4,6-Dichloro-5-fluoropyrimidine. This compound has unique chemical properties. The synthetic route is as follows.
Intermediate A33-5 (200mg, 0.94mmol) was dissolved in tetrahydrofuran (10mL), was added 4,6-dichloro-5-fluoropyrimidine (160mg, 0.96mmol),Diisopropylethyl amine (360mg, 2.79mmol), 50 stirred overnight, cooled to room temperature, spin dry solvent, the residue was purified by column chromatography (dichloromethane:Methanol = 50: 1) to give a white solid (220mg, 68%).
According to the analysis of related databases, 213265-83-9, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Suzhou Yunxuan Pharmaceutical Co., Ltd.; Zhang, Xiaohu; (54 pag.)CN105254613; (2016); A;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia