Adding a certain compound to certain chemical reactions, such as: 20924-05-4, 2-(5-Methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)acetic acid, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, 20924-05-4, blongs to pyrimidines compound. COA of Formula: C7H8N2O4
EXAMPLE 64. 1-(4-METHYL-THIAZOLE-2-SULFONYL)-4-[(THYMIN-1-YL)-ACETYL]-PIPERAZIN-2- one [00377] To 3 mL of DMF, were added 0.30 g (0.8 mmol) OF 4- (4-METHYL-THIAZOLE-2-SULFONYL)- piperazin-2-one trifluoroacetic acid salt, 0.147 g (0.8 mmol) of (thymin-1-yl)-acetic acid and 0.458 g of PYBOP. The reaction mixture was stirred for 4hours at room temperature. Almost of the solvent was removed in vacuo and the residue was dissolved in methylene chloride. The solution was washed with saturated sodium bicarbonate solution, water, 1N HCI, water and brine sequencially. The organic layer was concentrated and column chromatographed on silicagel to give 0.19 g (56%) OF THE title compound.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,20924-05-4, its application will become more common.
Reference:
Patent; PANAGENE INC.; WO2005/9998; (2005); A1;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia