In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 206564-00-3, name is 4-(2-Furyl)pyrimidin-2-amine, the common compound, a new synthetic route is introduced below. COA of Formula: C8H7N3O
To a solution of 4-(2-furyl)-2-pyrimidinylamine (4.10 g, 25.4 mmol) in N,N-dimethylformamide (40 ml) was added N-bromosuccinimide (4.53 g, 25.5 mmol) at 2C, followed by stirring as it was. After 6 hours, the reaction mixture was diluted with an aqueous saturated sodium bicarbonate solution (240 ml). The mixture was ice-cooled, and then the crystals were collected by filtration and washed with water, to give the title compound (5.10 g, 84%) as a pale brown solid.1H NMR (400 MHz, DMSO-d6) delta ppm; 6.73 (1H, dd, J = 1.6, 3.6 Hz), 6.96 (2H, br s), 7.50 (1H, dd, J = 0.8, 3.6 Hz), 7.97 (1H, dd, J = 0.8, 1.6 Hz), 8.41 (1H, s).
The synthetic route of 206564-00-3 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Eisai Co., Ltd.; EP1439175; (2004); A1;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia