Adding a certain compound to certain chemical reactions, such as: 101257-82-3, 4-Amino-5-chloropyrimidine, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, Computed Properties of C4H4ClN3, blongs to pyrimidines compound. Computed Properties of C4H4ClN3
59. (5-Chloro-pyrimidin-4-yl)-[4-(furan-2-ylmethylsulfanyl)-3-methyl-pyridin-2-ylmethyl]-amine The compound is obtained analogously to Example 40 from 4-amino-5-chloro-pyrimidine (1.34 g, 10.33 mmol) and 2-chloromethyl-4-(furan-2-ylmethylsulfanyl)-3-methyl-pyridine-hydrochloride (3.0 g, 10.33 mmol). The chromatography is done with toluene/ethyl acetate/methanol/conc. ammonia=6/3.5/0.5/0.01. The crude product is triturated with diethyl ether. Yield: 1.77 g (49%). Mp.: 169-170 C.
The synthetic route of 101257-82-3 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; BYK Gulden Lomberg Chemische Fabrik GmbH; US6395732; (2002); B1;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia