Adding a certain compound to certain chemical reactions, such as: 911461-47-7, 4,6-Dichloropyrimidine-5-carboxamide, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, HPLC of Formula: C5H3Cl2N3O, blongs to pyrimidines compound. HPLC of Formula: C5H3Cl2N3O
The compound 4,6-dichloropyrimidine-5-carboxamide (1.65 g, 8.6 mmol) was dissolved in methanol (30 mL) and then treated withSodium methoxide (1.15 g, 21.3 mmol) was added thereto, and the mixture was heated to 40 C and the reaction was stirred for 12 hours. Then, the mixedThe material was filtered, and the filtrate was concentrated under reduced pressure. The resulting residue was purified by silica gel column chromatography (pure EtOAc) to give the title compound asWhite solid (1.30 g, 83%).
The synthetic route of 911461-47-7 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Guangdong Dongyangguang Pharmaceutical Co., Ltd.; Jiatuo Sciences Corporation; Xi Ning; Wang Liang; Wu Zuping; Feng Xuejin; Wu Yanjun; (154 pag.)CN104513235; (2017); B;,
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