The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 911461-47-7, name is 4,6-Dichloropyrimidine-5-carboxamide. This compound has unique chemical properties. The synthetic route is as follows. SDS of cas: 911461-47-7
To a solution of 4,6-dichloropyrimidine-5-carboxamide (24.6 g, 128 mmol) in methanol (200 mL) was added a solution of sodium methylate (15.2 g, 282 mmol) in MeOH (100 mL). The resulted mixture was stirred at rt for 4.5 hours and concentrated in vacuo. The residue was purified by a silica gel column chromatography (EtOAc/MeOH (v/v)=25/1) to give the title compound as a pale yellow solid (18.3 g, yield: 71.1%). [0686] MS (ESI, pos. ion) mz: 184.1 [M+H]+; [0687] 1H NMR (600 MHz, CDCl3) delta (ppm): 8.47 (s, 1H), 6.30 (br. s, 1H), 5.98 (br. s, 1H), 4.07 (s, 6H).
With the rapid development of chemical substances, we look forward to future research findings about 911461-47-7.
Reference:
Patent; CALITOR SCIENCES, LLC; SUNSHINE LAKE PHARMA CO., LTD.; Xi, Ning; Wang, Liang; Wang, Tingjin; US2015/87658; (2015); A1;,
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