Introduction of a new synthetic route about 13053-88-8

At the same time, in my other blogs, there are other synthetic methods of this type of compound,13053-88-8, N-(Pyrimidin-2-yl)acetamide, and friends who are interested can also refer to it.

Adding a certain compound to certain chemical reactions, such as: 13053-88-8, N-(Pyrimidin-2-yl)acetamide, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, COA of Formula: C6H7N3O, blongs to pyrimidines compound. COA of Formula: C6H7N3O

A solution of 2-ampy (0.15 g, 1.59 mmol) in ethanol (10 cm3)was added to a solution of Na2PdCl4 (0.234 g, 0.796 mmol) inmethanol (10 cm3). The mixture was stirred at room temperaturefor 2 h. The yellow solid thus formed was filtered off, washed withmethanol and dried under vacuum 3: Yellow solid, 95%. Anal. Calc. for C12H14N6O2PdCl2: C, 31.9; H,3.1; N, 18.6. Found: C, 32.0; H, 3.4; N, 18.3%. IR: 3267m, 3227m,3078m, 2925m, 1693s, 1517m, 516m, 355m cm1. 1H NMR(DMSO-d6): d 10.55 (s, 2H, NH), 8.63 (d, 1H, pym-H), 7.15 (t, 1H,pym-H), 2.16 (s, 2H, CH3) ppm, 3J(HH) = 4.8 Hz. Melting point:234-236 C.

At the same time, in my other blogs, there are other synthetic methods of this type of compound,13053-88-8, N-(Pyrimidin-2-yl)acetamide, and friends who are interested can also refer to it.

Reference:
Article; Al-Jibori, Subhi A.; Al-Jibori, Qusay K.A.; Schmidt, Harry; Merzweiler, Kurt; Wagner, Christoph; Hogarth, Graeme; Inorganica Chimica Acta; vol. 402; (2013); p. 69 – 74;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia