So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Wei, Yunlong; Zhang, Hong; Wu, Xinxin; Zhu, Chen researched the compound: 5-Methylfuran-2(3H)-one( cas:591-12-8 ).Reference of 5-Methylfuran-2(3H)-one.They published the article 《Alkene Difunctionalization Triggered by a Stabilized Allenyl Radical: Concomitant Installation of Two Unsaturated C-C Bonds》 about this compound( cas:591-12-8 ) in Angewandte Chemie, International Edition. Keywords: radical alkynylalkenylation enynylalkenylation alkenes dual function sulfone reagent; alkene difunctionalization; alkyne; allenyl radical; radical reactions; rearrangement. We’ll tell you more about this compound (cas:591-12-8).
Radical-mediated difunctionalization of alkenes provides a promising approach to introduce one alkenyl or alkynyl group to target compounds However, simultaneous installation of two unsaturated C-C bonds via alkene difunctionalization remains elusive, attributable to the high instability and transient lifetimes of alkenyl and alkynyl radicals. Herein, we report the photocatalytic 1,2-alkynylalkenylation and 1,2-enynylalkenylation of alkenes for the first time, triggered by the intermol. addition of a stabilized allenyl radical to an alkene. A portfolio of strategically designed, easily accessible dual-function reagents are applied to a radical docking-migration cascade. The protocol has broad substrate scope and efficiently increases the degree of unsaturation
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Reference:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia