Romaniszyn, Marta; Gronowska, Katarzyna; Albrecht, Lukasz published the article 《Remote Functionalization of 4-(Alk-1-en-1-yl)-3-Cyanocoumarins via the Asymmetric Organocatalytic 1,6-Addition》. Keywords: dihydrofuranyl ethyl oxo chromene carbonitrile preparation diastereoselective enantioselective regioselective; alkenyl cyanocoumarin furanone organocatalytic addition.They researched the compound: 5-Methylfuran-2(3H)-one( cas:591-12-8 ).Recommanded Product: 5-Methylfuran-2(3H)-one. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:591-12-8) here.
An organocatalytic 1,6-addition using 4-(alk-1-en-1-yl)-3-cyanocoumarins as acceptors was developed. Dienolates derived from 5-substituted-furan-2(3H)-ones have been employed as pronucleophiles, therefore, enabling the synthesis of hybrid mols. bearing two biol. relevant units I [R = H, 7-MeO, 6-Br, etc.; R1 = Me, allyl, Ph, etc.; R2 = H, Me; R3 = H, Me]. Appropriate design of substrates and the application of quinine-derived catalyst resulted in very good site-selectivity as well as chem. and stereochem. efficiency of the process.
Compound(591-12-8)Recommanded Product: 5-Methylfuran-2(3H)-one received a lot of attention, and I have introduced some compounds in other articles, similar to this compound(5-Methylfuran-2(3H)-one), if you are interested, you can check out my other related articles.
Reference:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia