Introduction of a new synthetic route about 18436-73-2

This literature about this compound(18436-73-2)COA of Formula: C10H8ClNhas given us a lot of inspiration, and I hope that the research on this compound(4-Chloro-8-methylquinoline) can be further advanced. Maybe we can get more compounds in a similar way.

So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Landge, Vinod G.; Sahoo, Manoj K.; Midya, Siba P.; Jaiswal, Garima; Balaraman, Ekambaram researched the compound: 4-Chloro-8-methylquinoline( cas:18436-73-2 ).COA of Formula: C10H8ClN.They published the article 《Well-defined palladium(II) complexes for ligand-enabled C(sp3)-alkynylation》 about this compound( cas:18436-73-2 ) in Dalton Transactions. Keywords: palladium catalyst alkynylation methylquinoline; quinoline methyl alkynylation palladium catalyst. We’ll tell you more about this compound (cas:18436-73-2).

The first example of ligand-enabled C(sp3)-alkynylation of 8-methylquinoline is reported. The reaction is catalyzed by well-defined Pd(II) complexes. The present C(sp3)-alkynylation has a broad substrate scope as well as functional group tolerance and proceeds efficiently under mild conditions.

This literature about this compound(18436-73-2)COA of Formula: C10H8ClNhas given us a lot of inspiration, and I hope that the research on this compound(4-Chloro-8-methylquinoline) can be further advanced. Maybe we can get more compounds in a similar way.

Reference:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia