Synthetic Route of C10H8ClN. The mechanism of aromatic electrophilic substitution of aromatic heterocycles is consistent with that of benzene. Compound: 4-Chloro-8-methylquinoline, is researched, Molecular C10H8ClN, CAS is 18436-73-2, about Nucleophilic substitution reaction of chloroquinolines with 1,2,4-triazole. I. Synthesis of 4-(1H-1,2,4-triazol-1-yl)quinolines. Author is Korodi, Ferenc.
Synthesis of 4-(1H-1,2,4-triazol-1-yl)quinolines by the reaction of 4-chloroquinolines with 1,2,4-triazole was studied under neutral, acidic and basic reaction conditions. The significant role of acid and base catalysis as well as substituent effects on the reactivity of 4-chloroquinolines in these reactions are reported.
As far as I know, this compound(18436-73-2)Synthetic Route of C10H8ClN can be applied in many ways, which is helpful for the development of experiments. Therefore many people are doing relevant researches.
Reference:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia