So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Singh, Nitesh; Mansoori, Aadil; Jiwani, Gitanjali; Solanke, Amolkumar U.; Thakur, Tarun K.; Kumar, Rakesh; Chaurasiya, Mona; Kumar, Anirudh researched the compound: 5-Methylfuran-2(3H)-one( cas:591-12-8 ).Name: 5-Methylfuran-2(3H)-one.They published the article 《Antioxidant and antimicrobial study of Schefflera vinosa leaves crude extracts against rice pathogens》 about this compound( cas:591-12-8 ) in Arabian Journal of Chemistry. Keywords: Xanthomonas Magnaporthe Schefflera leaf histone deacetylase antioxidant antimicrobial. We’ll tell you more about this compound (cas:591-12-8).
Plant extracts are one of the best possible sources of bioactive mols., and are being used globally as an antioxidants and natural antimicrobial compounds In current study, Schefflera vinosa leaves extract was prepared through Soxhlet extraction procedure using methanol and chloroform as solvents. The extract was investigated for total antioxidant, phenolic and flavonoid contents, free radical scavenging and antimicrobial activities. The free radical scavenging activities were evaluated through 2,2- diphenyl-1-picrylhydrazyl (DPPH), 2,2-azino-bis-3-ethylbenzotiazolin-6-sulfonic acid (ABTS) and Ferric-reducing/ antioxidant power (FRAP) assay. The antimicrobial activity of extract was determined through poisoned food method. The methanolic extract has exhibited high antioxidant, phenolic, and flavonoid activities compared to chloroform extract Similarly, free radical scavenging activities (ABTS, DPPH and FRAP) were higher in methanolic extract Further, Fourier-Transform IR Spectroscopy (FTIR) used to determine the functional group and Gas chromatog.-mass spectrometry (GC-MS) to elucidate volatile composition of the crude extract Different functional group like N-H, O-H, C-O, C-N, C-H, C=O, C≃C and C-O-H presence indicate the existence of many metabolites in the extracts GC-MS study identified 61 compounds and subsequently, these mols. were screened virtually using DockThor. Furthermore, antimicrobial study was confirmed against rice pathogens like Magnaporthe oryzae (M. oryzae) and Xanthomonas oryzae pv. oryzae (Xoo). Mol. docking study further suggested that phytomols. (3-Isopropoxy-1,1,1,7,7,7-hexamethyl-3,5,5-tris (trimethylsiloxy) tetrasiloxane, and 2-Methoxy-5-methylthiophene) targets Histone Deacetylase (HDAC) of M. oryzae and Peptide Deformylase (PDF) of Xoo, which could inhibit their growth. Hence, this study indicated that Schefflera vinosa extracts could be an important ingredient as an antioxidant as well as antimicrobial agent against rice pathogens.
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Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia