Crigg, Ronald;Myers, Peter;Somasunderam, Anoma;Sridharan, Visuvanathar published 《X:Y-ZH systems as potential 1,3-dipoles. Part 36. 1,5-Electrocyclization processes via oxidation of tertiary amines. Pyrrolodihydroisoquinolines and -dihydro-β-carbolines》. The research results were published in《Tetrahedron》 in 1992.Electric Literature of C5H5ClN2O2 The article conveys some information:
A range of tertiary N-allylamines, e.g. I, derived from 1,2,3,4-tetrahydroisoquinoline undergo oxidative cyclization induced by Ag2CO3 to give pyrrolodihydroisoquinolines, e.g., II, in moderate to good yield. Analogous oxidative cyclizations are reported for N-allyltetrahydro-β-carbolines and a pyrrolidine. The reactions proceed via formation of a 1,5-dipole followed by an electrocyclization and subsequent aromatization. And 6-(Chloromethyl)pyrimidine-2,4(1H,3H)-dione (cas: 18592-13-7) was used in the research process.
6-(Chloromethyl)pyrimidine-2,4(1H,3H)-dione (cas: 18592-13-7 Electric Literature of C5H5ClN2O2) was used in the synthesis of: 5-bromo-6-(chloromethyl)uracil, pteridine compounds, potential anticancer agents, substituted uracil pyridinium compounds, potential inhibitors of thymidine phosphorylase.
Reference:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia