Janietz, D.;Goldmann, B.;Rudorf, W. D. published 《Chloromethyl substituted heterocycles from methyl chlorotetrolate》. The research results were published in《Journal fuer Praktische Chemie (Leipzig)》 in 1988.Related Products of 18592-13-7 The article conveys some information:
Reaction of ClCH2CCCO2Me with RNHCR1:NH (R = H, Ph, R1 = SMe; R = H, R1 = Ph, 4-O2NC6H4) gave pyrimidones I which were hydrolyzed to the uracils. Thiazinones II (R2 = H, Me, Et) were similarly prepared from R2NHCSNH2 and were hydrolyzed to the diones. Isomeric chloromethylthiazolopyrimidinones were obtained from ClCH2CCCO2Me or ClCH2COCH2CO2Et and aminothiazoles. An imidazothiazinone was similarly obtained from the mercaptoimidazole. And 6-(Chloromethyl)pyrimidine-2,4(1H,3H)-dione (cas: 18592-13-7) was used in the research process.
6-(Chloromethyl)pyrimidine-2,4(1H,3H)-dione (cas: 18592-13-7 Related Products of 18592-13-7) was used in the synthesis of: 5-bromo-6-(chloromethyl)uracil, pteridine compounds, potential anticancer agents, substituted uracil pyridinium compounds, potential inhibitors of thymidine phosphorylase.
Reference:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia