Pyrimidine is an aromatic heterocyclic organic compound similar to pyridine. One of the three diazines (six-membered heterocyclics with two nitrogen atoms in the ring), it has the nitrogen atoms at positions 1 and 3 in the ring. 109-12-6, formula is C4H5N3, Name is Pyrimidin-2-amine. The pyrimidine ring system has wide occurrence in nature as substituted and ring fused compounds and derivatives, including the nucleotides cytosine, thymine and uracil, thiamine (vitamin B1) and alloxan. Recommanded Product: Pyrimidin-2-amine.
Deng, Tianning;Mazumdar, Wrickban;Yoshinaga, Yuki;Patel, Pooja B.;Malo, Dana;Malo, Tala;Wink, Donald J.;Driver, Tom G. research published 《 Rh2(II)-Catalyzed Intermolecular N-Aryl Aziridination of Olefins using Nonactivated N-Atom Precursors.》, the research content is summarized as follows. The development of the first intermol. Rh2(II)-catalyzed aziridination of olefins using anilines as nonactivated N atom precursors and an iodine(III) reagent as the stoichiometric oxidant was reported. This reaction required the transfer of an N-aryl nitrene fragment from the iminoiodinane intermediate to a Rh2(II)-carboxylate catalyst; in the absence of a catalyst only diaryldiazene formation was observed This N-aryl aziridination was general and was successfully realized using as little as 1 equiv of the olefin. Di-, tri- and tetrasubstituted cyclic- or acyclic olefins was employed as substrates and a range of aniline- and heteroarylamine N atom precursors were tolerated. The Rh2(II)-catalyzed N atom transfer to the olefin was stereospecific, chemo- and diastereoselective to produce the N-aryl aziridine as the only amination product. Because the chem. of nonactivated N-aryl aziridines was underexplored, the reactivity of N-aryl aziridines was explored toward a range of nucleophiles to stereoselectively access privileged 1,2 stereodiads unavailable from epoxides, and removal of the N-2,4-dinitrophenyl group was demonstrated to show that functionalized primary amines was constructed.
109-12-6, 2-Aminopyrimidine is a useful research compound. Its molecular formula is C4H5N3 and its molecular weight is 95.1 g/mol. The purity is usually 95%.
2-Aminopyrimidine is an organic compound that belongs to the group of pyridines. It has been shown to have antimicrobial, antitumor, and antiviral properties. 2-Aminopyrimidine has been used as a fungicide and herbicide in horticulture and agriculture, respectively. The molecular geometry of this molecule is octahedral with coordination geometry C2v. This chemical binds to the BCR-ABL kinase receptor and inhibits its activity by competitive inhibition of ATP binding. 2-Aminopyrimidine has been shown to have a hematologic response in vivo models and in vitro assays. It also has anti-inflammatory effects when it is taken orally or applied topically., Recommanded Product: Pyrimidin-2-amine
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia