Homon, Anton A.; Hryshchuk, Oleksandr V.; Trofymchuk, Serhii; Michurin, Oleg; Kuchkovska, Yuliya; Radchenko, Dmytro S.; Grygorenko, Oleksandr O. published the artcile< Synthesis of 3-Azabicyclo[3.2.0]heptane-Derived Building Blocks via [3+2] Cycloaddition>, Application In Synthesis of 6554-61-6, the main research area is azabicyclo heptane derivative; cyclobuteneraboxylic acid ester cycloaddition.
An efficient approach to synthesis of various substituted 3-azabicyclo[3.2.0]heptane-derived building blocks based on [3+2] cycloaddition of cyclobut-1-eneraboxylic acid ester and in situ generated azomethine ylide was developed and applied on multigram scale. The utility of 1,3-disubstituted 3-azabicyclo[3.2.0]heptane scaffold was demonstrated by addnl. structural anal. using exit vector plot (EVP) tool, and tested in parallel synthesis of compound library.
European Journal of Organic Chemistry published new progress about [3+2] Cycloaddition reaction. 6554-61-6 belongs to class pyrimidines, and the molecular formula is C4H2Cl2N2, Application In Synthesis of 6554-61-6.
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia