《An efficient synthesis of designed 4-thiazolidinone fused pyrimidine derivatives as potent antimicrobial agents》 was written by Patel, Janki J.; Morja, Mayur I.; Chikhalia, Kishor H.. Name: 2,4,6-Trichloropyrimidine And the article was included in Journal of Heterocyclic Chemistry in 2020. The article conveys some information:
A novel series of hybrid 2-substituted [(pyrimidin-2-yl)hydrazinyl]thiazolidin-4-one derivatives I [R = H, 3-Cl, 4-NO2, etc.] was synthesized via aromatic nucleophilic displacement of chlorine atoms/intermol. cyclization of 2-chloro-N’-[6-morpholino-4-[(substituted-phenyl)amino]pyrimidin-2-yl]acetohydrazides II with ammonium thiocyanate. I were evaluated for their antibacterial and antifungal activities against various strains of bacteria and fungi. Structure-activity relationship and HOMO-LUMO studies were also carried out for confirming structure-biol. activity. Thus, these studies suggested that hydrazinyl pyrimidine derivatives I bearing a thiazolidinone moiety are interesting scaffolds for the development of novel antimicrobial agents. After reading the article, we found that the author used 2,4,6-Trichloropyrimidine(cas: 3764-01-0Name: 2,4,6-Trichloropyrimidine)
2,4,6-Trichloropyrimidine(cas: 3764-01-0) is a member of organic chlorides. Organic chloride content in crude oil can be detected through specialized laboratory analysis. Care and attention are essential while sampling and testing.Name: 2,4,6-Trichloropyrimidine
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia