《An efficient and scalable approach for the synthesis of piperazine based glitazone and its derivatives》 was published in Synthetic Communications in 2020. These research results belong to Sharma, Vijay Kumar; Barde, Anup; Rattan, Sunita. SDS of cas: 3934-20-1 The article mentions the following:
A versatile and efficient synthetic approach has been developed for the synthesis of piperazine based glitazones I (R = Me, propan-2-yl, cyclopropylmethyl, etc.) analogus to Lobeglitazone. Desired compounds I were synthesized with good yields by alkylation of piperazine substrate I (R = H) with various carbonyl compds R1C(O)R2 (R1 = H, Me, Et, cyclopropyl; R2 = H, Me; R1R2 = -(CH2)3-). This substrate has the potential for the construction of novel heterocyclic compounds with medicinal importance. In the experimental materials used by the author, we found 2,4-Dichloropyrimidine(cas: 3934-20-1SDS of cas: 3934-20-1)
2,4-Dichloropyrimidine(cas: 3934-20-1) is a member of organic chlorides. Almost all organochlorine compounds are synthesized. It is widely used as intermediates, solvents and pesticides of chemical synthetic products.SDS of cas: 3934-20-1
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia