In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 113583-35-0, name is 2-Methanesulfonyl-4,6-dimethoxypyrimidine, the common compound, a new synthetic route is introduced below. Application In Synthesis of 2-Methanesulfonyl-4,6-dimethoxypyrimidine
Add (10mmol) salicylaldehyde, (10mmol) 4,6-dimethoxy-2-methylsulfonylpyrimidine, (20mmol) potassium carbonate powder, and 30ml DMF into a 100ml three-necked flask equipped with a reflux condenser. Gradually heat to 60C, stir the reaction for 1 to 3 hours, and track the reaction to the end by TLC.Stop the reaction, transfer the reaction system to 100ml of water while it is hot, and stir it fully to precipitate a white or light yellow solid, with a yield of 92%, mp 91-92C, without purification, and directly used in the next reaction.
The synthetic route of 113583-35-0 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Xi’an Modern Chemical Institute; Wang Wei; Wang Lieping; Li Bingbo; Zhang Xiaoguang; Liu Kangyun; Ning Binke; Xue Chao; (10 pag.)CN111269223; (2020); A;,
Pyrimidine | C4H4N2 – PubChem,
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