A new synthetic route of 2-Chloro-4-phenylpyrimidine

The synthetic route of 13036-50-5 has been constantly updated, and we look forward to future research findings.

Synthetic Route of 13036-50-5 , The common heterocyclic compound, 13036-50-5, name is 2-Chloro-4-phenylpyrimidine, molecular formula is C10H7ClN2, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route.

Man erhitzte 0, 80 g (4, 20 MMOL) 2-CHLOR-4-PHENYLPYRIMIDIN AUS BEISPIEL 24. 1 in 3, 20 ml konz. HCI 1 Stunde auf 100 C. Anschliessend engte man den Ansatz ein, suspendierte ihn in Methylenchlorid und engte erneut ein. Ausbeute : 0, 83 g. ESI-MS : 174, 3, [M+H+] = 173, 2 ;

The synthetic route of 13036-50-5 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; ABBOTT GMBH & CO. KG; WO2004/80981; (2004); A1;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia