Electric Literature of 1192711-71-9, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 1192711-71-9, name is 2,4-Dichloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidine. This compound has unique chemical properties. The synthetic route is as follows.
This compound was prepared following a similar protocol as that presented for Compound 57, except that the starting material used was 2,6-dichloro-8-methyl-7-deazapurine. Briefly, 2,6- dichloro-8-methyl-7-deazapurine (50 mg, 0.25 mmol) was suspended in 1-butanol (3 mL), and DCM (2 mL) was added dropwise until the suspension became a clear solution at room temperature. Pyrrolidine (0.55 mmol) was then added slowly, and the reaction was stirred overnight until TLC analysis (DCM: MeOH 2.5%) indicated it was complete. The mixture was concentrated and the residue dissolved in DCM (20 mL), and the resulting solution was washed with water (2 x 3 mL) to remove the hydrochloride. The solution was then dried over anhydrous Na2S04 and purified by silica gel column chromatography to afford Compound 58 (55 mg, 94% yield); LC-MS m/z = 237.1 [M+l], corresponding CnHi3ClN4.
While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 1192711-71-9, 2,4-Dichloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidine.
Reference:
Patent; SPEROVIE BIOSCIENCES, INC.; IYER, Radhakrishnan, P.; SHERI, Anjaneyulu; PADMANABHAN, Seetharamaiyer; GIMI, Rayormand, H.; CLEARY, Dillon; KHEDKAR, Santosh; CHALLA, Sreerupa; (121 pag.)WO2017/123766; (2017); A1;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia