A new synthetic route of 43024-61-9

The chemical industry reduces the impact on the environment during synthesis 43024-61-9, I believe this compound will play a more active role in future production and life.

Electric Literature of 43024-61-9, With the rapid development and complex challenges of chemical substances, the synthesis of new drugs is usually one of the most effective ways to increase yield.43024-61-9, name is Ethyl 7-hydroxypyrazolo[1,5-a]pyrimidine-6-carboxylate, molecular formula is C9H9N3O3, molecular weight is 207.19, as common compound, the synthetic route is as follows.

(a) 7-Hydroxypyrazolo[1,5-a]pyrimidine-6-carboxylic acid A mixture of ethyl 7-hydroxypyrazolo[1,5-a]pyrimidine-6-carboxylate (0.50g., 2.4mM) and 10% sodium hydroxide solution (5ml) was heated on a steam bath for 3 hours. The reaction mixture was cooled and acidified with acetic acid to give the required product as white crystals in 76.3% weight yield (0.33%), m.p. 319-320 C (decomposition), numax (nujol) 1740 (acid C=O) and 1675 (lactam C=O)cm-1.

The chemical industry reduces the impact on the environment during synthesis 43024-61-9, I believe this compound will play a more active role in future production and life.

Reference:
Patent; Beecham Group Limited; US4081545; (1978); A;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia