Related Products of 61727-33-1, In the chemical reaction process,reaction time,type of solvent,can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product.An updated downstream synthesis route of 61727-33-1 as follows.
(0234) To a solution of 5-chloro-2-(methylthio)pyrimidine-4-carboxylic acid (1.026 g, 5.02 mmol) in 1:1 DCM:methanol was added a solution of trimethylsilyldiazomethane (2M/hexanes, 1.6 mL, 3.2 mmol). The reaction was stirred at RT for 30 min and then concentrated to give the desired 29-1, which was used without further purification. MS (ESI): mass calcd. for C7H7ClN2O2S, 218.0; m/z found 219.1 [M]+.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,61727-33-1, its application will become more common.
Reference:
Patent; Sunesis Pharmaceuticals, Inc.; HANSEN, Stig; ERLANSON, Dan; CANCILLA, Mark; EP2257637; (2015); B1;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia