Pollution characterization of pharmaceutically active compounds (PhACs) in the northwest of Tai Lake Basin, China: Occurrence, temporal changes, riverine flux and risk assessment was written by An, Wenkai;Duan, Lei;Zhang, Yizhe;Zhou, Yitong;Wang, Bin;Yu, Gang. And the article was included in Journal of Hazardous Materials in 2022.HPLC of Formula: 1220-83-3 This article mentions the following:
PhACs have attracted great attentions of researchers because of their potential ecol. and healthy risks. However, their long-term pollution tendency study is very scarce. In this study, 32 target PhACs from surface water, wastewater treatment plants, fishponds and livestock farms were investigated in Wujin, a city located in the northeast of Tai Lake, using grab sampling. The occurrence, spatiotemporal distribution characteristics, potential sources, riverine flux and risk assessment were systematically analyzed. It was found that non-antibiotics were the mainly PhACs category in Wujin and CF, SMX were the predominant non-antibiotics and antibiotics, resp. Besides, the average concentrations of total PhACs were 586.6 ng L-1 and 273.2 ng L-1 in 2018 and 2019, resp. This improvement could be mainly attributed to the closure of fishponds and livestock farms. Moreover, CF/CBZ ratios which was considered as an indicator to trace untreated wastewater decrease significantly in 2019, and this was also a main reason for the improvement. Riverine flux could be calculated through arranging control sampling sites in the boundary and the net riverine inflow flux of PhACs in Wujin was 264.3 kg/a. Finally, CF, SMX, EM were evaluated as the high risk contaminants based on a comprehensive risk assessment method. In the experiment, the researchers used many compounds, for example, 4-Amino-N-(6-methoxypyrimidin-4-yl)benzenesulfonamide (cas: 1220-83-3HPLC of Formula: 1220-83-3).
4-Amino-N-(6-methoxypyrimidin-4-yl)benzenesulfonamide (cas: 1220-83-3) belongs to pyrimidine derivatives. The aromatic compound pyrimidine, and its derivatives, are ubiquitous in nature. They are found in nucleic acids, vitamins, amino acids, antibiotics, alkaloids, and a variety of toxins. Therapy for fungal infections is based mainly on four classes of antifungals: azoles, echinocandins, polyenes, and pyrimidine analogs.HPLC of Formula: 1220-83-3
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia