In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 5604-46-6, name is 2-Amino-4,6-dichloropyrimidine-5-carbaldehyde, the common compound, a new synthetic route is introduced below. Recommanded Product: 5604-46-6
2.1 Preparation of 2-Amino-4-chloro-6-dibenzylamino-5-pyrimidine Carbaldehyde 2-Amino-4,6-dichloro-5-pyrimidine carbaldehyde (0.15 g; 0.78 mmol) prepared as in Scheme 1 was stirred in dry dichloromethane (3 ml) at 0 C. Dibenzylamine (1 eq; 0.78 mmol; 0.154 g) and triethylamine (1 eq; 0.78 mmol; 0.078 g) were added dropwise. The reaction was allowed to reach r.t, and stirred overnight by which time a clear solution had been obtained. Further dichloromethane (50 ml) was added and the solution washed with saturated sodium chloride solution and water. _:The organic layer was dried and evaporated leaving a yellow solid (0.253 g; 0.72 mmol; 92.3%). M.p. 138-142 C.
The synthetic route of 5604-46-6 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Cancer Research Campaign Technology Limited; US6677345; (2004); B1;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia