2380-63-4, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 2380-63-4, name is 1H-Pyrazolo[3,4-d]pyrimidin-4-amine. This compound has unique chemical properties. The synthetic route is as follows.
1 H-Pyrazolo[3,4-d]pyrimidin-4-amine (20. Og, 148.01 mmol) and /V-iodosuccinimide (60.61 g, 222.01 mmol) were combined in DMF (200mL) and the mixture heated to 80C, under nitrogen, overnight. The bulk of the solvent was removed under reduced pressure and the residue was allowed to cool and stand for a couple of hours. The resultant material was stirred in warm water (250 ml), filtered off and washed with methanol (3 x 150 ml) to give 3-iodo-1 /-/-pyrazolo[3,4-c ]pyrimidin-4-amine (20.92g, 80.147mmol, 54.1 % yield) LCMS (ES+, short acidic): ~0.35-0.65 min, m/z 262 [M+H]+ NMR (d6 DMSO): 13.8 (s, 1 H), 8.21 (s, 1 H), 7.20 (bs, 2H).
Statistics shows that 2380-63-4 is playing an increasingly important role. we look forward to future research findings about 1H-Pyrazolo[3,4-d]pyrimidin-4-amine.
Reference:
Patent; REDX PHARMA LIMITED; ARMER, Richard; BINGHAM, Matilda; MORRISON, Angus; CARSWELL, Emma; ELUSTONDO, Fred; WALKER, Rolf; GUISOT, Nicolas; LUCAS, Catherine; WO2014/188173; (2014); A1;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia