Electric Literature of 330786-24-8, Adding some certain compound to certain chemical reactions, such as: 330786-24-8, name is 3-(4-Phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine,molecular formula is C17H13N5O, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 330786-24-8.
9g tri-n-butylphosphine dissolved in 100mL anhydrous tetrahydrofuran and cooled down to 0-5 degrees.9g of diisopropyl azodicarboxylate was added dropwise under N2 protection. After the addition was completed,The reaction temperature was controlled at 0-5 degrees for 1 h. The above tributylphosphine andA mixture of diisopropyl azodicarboxylate was slowly poured into 4 g of solution3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine andIn 3.5 g of (S)-1-Boc-3-hydroxypiperidine in 50 mL of anhydrous tetrahydrofuran,Stir 0-5 degrees overnight. After the reaction liquid is concentrated under reduced pressure,Purification by column to obtain the product 6.8g, yield 75%
According to the analysis of related databases, 330786-24-8, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Shanghai Fupu Biological Technology Co., Ltd.; Liu Zheng; (13 pag.)CN106279284; (2017); A;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia