Adding a certain compound to certain chemical reactions, such as: 3438-46-8, 4-Methylpyrimidine, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, SDS of cas: 3438-46-8, blongs to pyrimidines compound. SDS of cas: 3438-46-8
A mixture of 4-methylpyrimidine (22) (10 g, 106 mmol), N,Ndimethylformamidedimethylacetal (DMFDMA) (38 g, 319 mmol)and DMF (46.6 g, 637 mmol) was stirred in a sealed-tube at140 C for 24 h. After cooling, the solution was evaporated in vacuoto yield the title compound 23 (15.08 g, 95%). 1H NMR (CDCl3) d:8.73 (br s, 1H), 8.22 (d, J = 5.5 Hz, 1H), 7.77 (d, J = 12.9 Hz, 1H),6.72 (dd, J = 5.5, 12.9 Hz, 1H), 5.00 (d, J = 12.9 Hz, 1H), 2.96 (s, 6H).
The synthetic route of 3438-46-8 has been constantly updated, and we look forward to future research findings.
Reference:
Article; Hasumi, Koichi; Sato, Shuichiro; Saito, Takahisa; Kato, Jun-Ya; Shirota, Kazuhiko; Sato, Jun; Suzuki, Hiroyuki; Ohta, Shuji; Bioorganic and Medicinal Chemistry; vol. 22; 15; (2014); p. 4162 – 4176;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia