Synthetic Route of 6299-87-2, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 6299-87-2, name is 6-Hydroxypyrimidine-4-carboxylic acid. This compound has unique chemical properties. The synthetic route is as follows.
Step 2: 6-chloropyrimidine-4-carboxylic acid chloride 50.0 g (0.35 mol) 6-hydroxypyrimidine-4-carboxylic acid were taken and 500 mL phosphorus oxychloride were added. Then 150 g (0.72 mol) phosphorus pentachloride were added batchwise with stirring. The reaction mixture was refluxed for 5 h. The phosphorus oxychloride was distilled off and the residue was purified by vacuum distillation through a column. Yield: 51.9 g (83% of th.) MS: m/z=176/178/180 (M)+
While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 6299-87-2, 6-Hydroxypyrimidine-4-carboxylic acid.
Reference:
Patent; BOEHRINGER INGELHEIM INTERNATIONAL GMBH; US2011/21500; (2011); A1;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia