Adding a certain compound to certain chemical reactions, such as: 63200-54-4, 2,4-Dichloro-5H-pyrrolo[3,2-d]pyrimidine, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, COA of Formula: C6H3Cl2N3, blongs to pyrimidines compound. COA of Formula: C6H3Cl2N3
Dissolve 5H-pyrrolo[3,2-d]pyrimidine (510 mg, 1 eq) in acetone (10 ml) and add p-toluenesulfonyl chloride. (265 mg, 1.3 eq) and sodium hydroxide (1.3 eq) were reacted at room temperature for 2 h, added with water, extracted with dichloromethane, concentrated, and dried to give a solid. (302 mg, 83%).
The synthetic route of 63200-54-4 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Jiangsu Xiansheng Pharmaceutical Co., Ltd.; Xin Minxing; Tang Feng; Wen Jun; Shen Han; Tu Chongxing; Zhao Xinge; (48 pag.)CN104177363; (2018); B;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia