Adding a certain compound to certain chemical reactions, such as: 799842-07-2, N-[5-Bromomethyl-4-(4-fluorophenyl)-6-isopropylpyrimidine-2-yl]-N-methylmethane sulfonamide, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, Formula: C16H19BrFN3O2S, blongs to pyrimidines compound. Formula: C16H19BrFN3O2S
39.68 grams of 5-methoxy-2-mercapto benzimidazole compound of formula-19b is added to aqueous sodium hydroxide solution(9.61 gm sodium hydroxide in 200 ml water) at 25 to 350C and stirred for 15 minutes, then added a solution of 400 ml of acetone and 100 grams of [4-(4-Fluoro phenyl) – 6 -isopropyl -2-(N-Methyl-N-methane Sulphonyl amino pyrimidine-5yl] methyl bromide compound of formula- 18a and stirred for 2 hours at 25 to 3O0C. Quenched the reaction mass with chilled water filtered the obtained precipitate and dried the compound at 60-650C for 3 hours to get the title compound. Yield: 110 grams. M.R: 159-163C.
The synthetic route of 799842-07-2 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; SATYANARAYANA REDDY, Manne; THIRUMALAI RAJAN, Srinivasan; SAHADEVA REDDY, Maramreddy; WO2007/125547; (2007); A2;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia