Reference of 20781-06-0, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 20781-06-0, name is 2,4-Diaminopyrimidine-5-carboxaldehyde. This compound has unique chemical properties. The synthetic route is as follows.
(5) Preparation of IA-1 (target): A mixture of 0.188 g (1 mmol) of compound of formula V and 0.447 g (1.5 mmol) of compound of formula III-1, 0.126 g (2 mmol) of sodium cyanoborohydride was added and maintained in a reflux state for 24 hours in 15 mL of methanol, The residue was purified by silica gel column chromatography (eluent: methanol: dichloromethane = 1: 10, and the residue was washed with ethyl acetate, washed with ethyl acetate, and the organic phase was washed with saturated brine. The organic phase was concentrated (the solvent was removed under reduced pressure) v / v) to give a white solid (IA-I) in 65% yield
According to the analysis of related databases, 20781-06-0, the application of this compound in the production field has become more and more popular.
Reference:
Patent; East China University of Science and Technology; Zhu Jin; Huang Jin; Chen Wenhua; Yao Xue; Ling Dazheng; Wang Manjiong; Jiang Hualiang; Li Jian; (21 pag.)CN106938997; (2017); A;,
Pyrimidine | C4H4N2 – PubChem,
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