Synthetic Route of 461-98-3, Adding some certain compound to certain chemical reactions, such as: 461-98-3, name is 2,6-Dimethylpyrimidin-4-amine,molecular formula is C6H9N3, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 461-98-3.
Preparation of the starting compound STR11 6.9 g (0.08 mol) of cyanoacetic acid and 10 g (0.08 mol) of 4-amino-2,6-dimethylpyrimidine are dissolved in 80 ml of pyridine, and 8.3 g (0.08 mol) of acetic anhydride are added. The pyridine is subsequently removed in vacuo, and the residue is taken up in toluene, concentrated, taken up a second time in toluene and again concentrated. The residue is chromatographed using ethyl acetate as eluent. 7.8 g (50.5% of theory) of 2,6-dimethyl-4-cyano-acetamido-pyrimidine of melting point 178 C. are obtained.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 461-98-3, 2,6-Dimethylpyrimidin-4-amine, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Bayer Aktiengesellschaft; US4886833; (1989); A;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia