Recommanded Product: Piperidin-4-amine dihydrochloride. The fused heterocycle is formed by combining a benzene ring with a single heterocycle, or two or more single heterocycles. Compound: Piperidin-4-amine dihydrochloride, is researched, Molecular C5H14Cl2N2, CAS is 35621-01-3, about The synthesis of a series of 7-amino-1-cyclopropyl-8-fluoro-1,4-dihydro-4-oxo-1,6-naphthyridine-3-carboxylic acids as potential antibacterial agents. Author is Sanchez, Joseph P.; Gogliotti, Rocco D..
A series of title compounds I [R = 3-aminopyrrolidin-1-yl, 3-(ethylaminomethyl)pyrrolidin-1-yl, 4-aminopiperidin-1-yl, piperazin-1-yl] was prepared and evaluated for antibacterial activity (no data). I were prepared by the displacement of the chloro substituent from I (R = Cl) with the requisite nitrogen nucleophile. The naphthyridine acid was synthesized in ten steps from pyridinecarboxylate II (R1 = OH, R2 = NO2). The key step in the sequence was a Schiemann reaction of II (R1 = Cl, R2 = N2+ PF6-) to give II (R1 = Cl, R2 = F).
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Reference:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia