Synthetic Route of 6299-25-8, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 6299-25-8, name is 4,6-Dichloro-2-(methylthio)pyrimidine. This compound has unique chemical properties. The synthetic route is as follows.
To a stirred solution of 4, 6-Dichloro-2-methylsulfanyl-pyrimidine 0103 (5.0 g, 25.6 mmol) in CH2Cl2 (15 mL) at 0 0C was added meta-chloroperoxybenzoic acid (11.06 g, 64.1 mmol) over a period of 20 minutes. The reaction was allowed to warm to room temperature and stirred for 2.5 hours. The mixture was filtrated and the filtrate was concentrated. The resulting residue was washed with saturated Na2CO3 solution and ether to form a white solid which was dried to obtain the title compound 0104 (2.6g, 44%): LCMS: 227 [M+l]+; 1H NMR (CDCl3) delta 3.4 (s, 3H), 7.75 (s, IH).
While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 6299-25-8, 4,6-Dichloro-2-(methylthio)pyrimidine.
Reference:
Patent; CURIS, INC.; WO2009/86012; (2009); A1;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia