The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 874-14-6, name is 1,3-Dimethyluracil. This compound has unique chemical properties. The synthetic route is as follows. Recommanded Product: 1,3-Dimethyluracil
General procedure: A 0.3M solution of Bu4NClO4 in THF (15 mL) was placed in thecathodic chamber of a divided cell (40 mL beaker, 3 cm diameter, 6 cm height)equipped with a lead cathode (5 X 5 cm2), a platinum anode (2 X 1 cm2),and a ceramic cylindrical diaphragm (1.5 cm diameter). A 0.3 M solution of Et4NOTsin DMF (4 mL) was placed in the anodic chamber (inside the diaphragm). 1,3-Dimethylpyrimidine-2,4(1H,3H)-dione(1a) (140 mg, 1.0 mmol), benzophenone (2a) (368mg, 2.0 mmol), TMSCl (0.64 mL, 5 mmol), and TEA (0.70 mL, 5 mmol) were added tothe cathodic chamber. After 400 C of electricity was passed at a constantcurrent of 200 mA at room temperature under nitrogen atmosphere, the catholytewas evaporated in vacuo. The residue was dissolved in diethyl ether (20 mL)and insoluble solid was filtered off. After removal of the solvent in vacuo, the residue was purified by column chromatography on silica gel(hexanes-EtOAc) to give 3a (305 mg) in 77percent yield.
With the rapid development of chemical substances, we look forward to future research findings about 874-14-6.
Reference:
Article; Kise, Naoki; Miyamoto, Hiroyuki; Hamada, Yusuke; Sakurai, Toshihiko; Tetrahedron Letters; vol. 56; 31; (2015); p. 4599 – 4602;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia