932-52-5, A common compound: 932-52-5, name is 5-Aminopyrimidine-2,4(1H,3H)-dione,molecular formula is C4H5N3O2, it can change the direction of chemical reaction, and react with certain compounds to generate new functional products. A new synthetic method of this compound is introduced below.
Equipped with a stirrer, thermometer, reflux condenser, the reaction vessel was added 1-amino-phthalide (2) 0.23mol, 5- aminouracil 0.28 mol, stannous chloride 0.31mol, 75% mass fraction cyclohexyl 230ml dioxane, stirred at 170 rpm and speed control, batches of 35% mass fraction of 0.13 mol sodium sulfite solution, the reaction was stirred 7H, filtered, and the filtrate was concentrated under reduced pressure the cyclohexane distilled off, added 630ml of 15% mass fraction of KCl , the precipitated solid was filtered, washed with sodium bromide solution, dried over anhydrous magnesium sulfate, was added to a mass fraction of 80% acetonitrile, and the solution temperature rises to 65 , 80min after filtration, the mass fraction of 95% nitromethane recrystallized to give crystals of 1- phthalide 5-amino-uracil 53.63g, yield 89%.
With the rapid development of chemical substances, we look forward to future research findings about 932-52-5.
Reference:
Patent; Chengdu Chester Technology Co., Ltd.; Peng, Fei; (5 pag.)CN105481837; (2016); A;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia