Application of Reference of 3029-64-9

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 3029-64-9, 2,4,6-Trichloro-5-cyanopyrimidine, other downstream synthetic routes, hurry up and to see.

Reference of 3029-64-9, Adding some certain compound to certain chemical reactions, such as: 3029-64-9, name is 2,4,6-Trichloro-5-cyanopyrimidine,molecular formula is C5Cl3N3, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 3029-64-9.

b 4-Chloro-2,6-bis-cyclopropylamino-pyrimidine-5-carbonitrile To a solution of 500 mg (2.4 mmol) of 2,4,6-trichloro-5-cyano-pyrimidine in 30 ml of dioxane were added at room temperature 0.84 ml (4.8 mmol) of N-ethyl-diisopropylamine and 0.52 ml (7.2 mmol) of cyclopropylamine. The yellow reaction mixture was stirred at room temperature during 18 hours, then, for working-up, it was evaporated under reduced pressure. The residue obtained was then chromatographed on silica gel using a 3:1 mixture of dichloromethane and hexane as the eluent yielding 328 mg (1.3 mmol, 55percent of theory) of 4-chloro-2,6-bis-cyclopropylamino-pyrimidine-5-carbonitrile as a yellow solid; MS: [M+H]+=249.

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 3029-64-9, 2,4,6-Trichloro-5-cyanopyrimidine, other downstream synthetic routes, hurry up and to see.

Reference:
Patent; Binggeli, Alfred; Maerki, Hans-Peter; Masquelin, Thierry; Mutel, Vincent; Wilhelm, Maurice; Wostl, Wolfgang; US2003/60466; (2003); A1;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia