Arya, V. P. published the artcilePsychoactive agents. Part VI. Synthesis and central nervous system effects of some 2-substituted 5-acetyl-4-methylpyrimidine derivatives, Product Details of C7H9N3O, the main research area is pyrimidine acetyl; central nervous system acetylpyrimidine; bactericide furylvinylpyrimidine.
The synthesis of 2-substituted 5-acetyl-4-methylpyrimidines is described. Thus, amidines and substituted guanidines react with EtOCH:C(COMe)2 to give the 5-acetyl-4-methyl-2-substituted pyrimidines I (R = NH2, MeS, morpholino, Ph, etc.). Aminolysis of I (R = MeS) with cyclic secondary amines gave I (R = piperidino, piperazino, pyrrolidino, etc.). Some of these amines were converted to their guanylhydrazones. Mannich condensation of I (R = morpholino) gave II. Some I had central nervous system and bactericidal activity.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry published new progress about Cyclocondensation reaction. 66373-25-9 belongs to class pyrimidines, name is 1-(2-Amino-4-methylpyrimidin-5-yl)ethanone, and the molecular formula is C7H9N3O, Product Details of C7H9N3O.
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia