In 1974,Journal of Organic Chemistry included an article by Banerjee, Sujit; Tee, Oswald S.. Safety of 5-Bromo-4,6-dihydroxypyrimidine. The article was titled 《Bromide ion induced debromination of the 5,5-dibromo derivatives of 4,6-dihydroxy pyrimidine and 6-methyluracil》. The information in the text is summarized as follows:
In aqueous solutions 4,6-dihydroxypyrimidine and 6-methyluracil react rapidly with 2 equiv of Br to yield first the corresponding 5-bromo compounds and second the 5,5-dibromo derivatives Under acidic conditions the latter compounds react with Br-to yield the monobromo derivatives and Br. The liberated Br is consumed in the presence of unreacted substrate to give a second equiv of the 5-bromopyrimidinedione. The kinetics of debromination were measured, and probable mechanisms for these processes were discussed. In the experimental materials used by the author, we found 5-Bromo-4,6-dihydroxypyrimidine(cas: 15726-38-2Safety of 5-Bromo-4,6-dihydroxypyrimidine)
5-Bromo-4,6-dihydroxypyrimidine(cas: 15726-38-2) belongs to pyrimidine. Pyrimidine nucleotide derivatives have a wide range of biological applications. For example, pyrimidine derivatives are useful in DNA repair studies involving cancer and epigenetics.Safety of 5-Bromo-4,6-dihydroxypyrimidine
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia