Hyperactive magnetically separable nano-sized MgFe2O4 catalyst for the synthesis of several five- and six-membered heterocycles was written by Bansal, Shobha;Kumar, Yogendra;Das, Dipak Kumar;Singh, Prabal Pratap. And the article was included in Chemistry & Chemical Technology in 2019.Recommanded Product: 40230-24-8 This article mentions the following:
MgFe2O4 nanoparticle ferrites were synthesized by combustion technique using pure ferric nitrate and magnesium nitratecarbonate. The magnetically separable MgFe2O4 MNP’s were found to be hyper active catalyst for the synthesis of a wide range of biol. active five and six-membered heterocyclic moieties at refluxing conditions. Reaction times were lowest in comparison to all reported in literature with excellent yields. Strong electron pull of Fe3+ was responsible for its hyper activity, which was substantiated by substitution of Fe3+ by other trivalent metal ions. Mg2+ contain a unique role because replacement of Mg2+ has poor catalytic activity. The developed protocol was efficiently utilized for the synthesis of a series of substituted mono/bis pyrimidines, pyrimidin-2-ol, pyrimidin-2-thiol, pyrazoles and isoxazoles by condensing monochalcones/1,4-bischalcones with various bis-nucleophiles in the presence of catalytic amount of heterogenous magnetic MgFe2O4 nanoparticles. The structure of these synthesized compounds was determined by FTIR, 1H, 13C and mass spectra. The catalyst was removed easily from reaction mixture by using a simple external magnet. Nanoparticles of ferrite were recovered and reused with no appreciable change in the activity even after the five runs. Nanoparticles were characterized by XRD, TEM and IR spectroscopy. In the experiment, the researchers used many compounds, for example, 4,6-Diphenylpyrimidin-2-amine (cas: 40230-24-8Recommanded Product: 40230-24-8).
4,6-Diphenylpyrimidin-2-amine (cas: 40230-24-8) belongs to pyrimidine derivatives. Pyrimidines are isomeric with two other forms of diazines: pyridazine, with the nitrogen atoms in the 1 and 2 positions; and pyrazine, with the nitrogen atoms in the 1 and 4 positions. A Cu-catalyzed and 4-HO-TEMPO-mediated [3 + 3] annulation of commercially available amidines with saturated ketones enables an efficient and facile synthesis of structurally important pyrimidines via a cascade reaction of oxidative dehydrogenation/annulation/oxidative aromatization.Recommanded Product: 40230-24-8
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia