Synthesis and Characterization of Verdazyl Radicals Bearing Pyridine or Pyrimidine Substituents: A New Family of Chelating Spin-Bearing Ligands was written by Barr, Christa L.;Chase, Preston A.;Hicks, Robin G.;Lemaire, Martin T.;Stevens, Cecilia L.. And the article was included in Journal of Organic Chemistry in 1999.SDS of cas: 16879-39-3 This article mentions the following:
The syntheses and characterization of two new 1,5-dimethyl-6-oxoverdazyl radicals bearing 2-pyridine and 4,6-dimethyl-2-pyrimidine rings as substituents are described. The radical precursors, the corresponding 1,2,4,5-tetrazanes, were prepared by condensation of the bis(1-methylhydrazide) of carbonic acid with the appropriate aromatic aldehyde. Oxidation of 3-(4,6-dimethyl-2-pyrimidyl)-1,5-dimethyl-1,2,4,5-tetrazane 6-oxide with sodium periodate afforded 1,5-dimethyl-3-(4,6-dimethyl-2-pyrimidyl)-6-oxoverdazyl, which could be isolated and stored without decomposition In contrast, attempts to oxidize the analogous 3-(2-pyridyl)-1,5-dimethyl-1,2,4,5-tetrazane 6-oxide with periodate produced 1,5-dimethyl-3-(2-pyridyl)-6-oxoverdazyl which could not be isolated. However, oxidation of this tetrazane with benzoquinone produced the pyridylverdazyl as a 1:1 complex with hydroquinone. This complex is indefinitely stable in the solid state and provides a means of long-term storage of the pyridylverdazyl. The electronic properties of both radicals have been characterized by EPR spectroscopy, cyclic voltammetry, and MNDO calculations The radicals have a wide electrochem. window of stability (>1.8 V), and the EPR and computational studies indicate a large spin d. residing on N2 and N4. In the experiment, the researchers used many compounds, for example, 2-Bromo-4,6-dimethylpyrimidine (cas: 16879-39-3SDS of cas: 16879-39-3).
2-Bromo-4,6-dimethylpyrimidine (cas: 16879-39-3) belongs to pyrimidine derivatives. The pyrimidine derivatives can easily interact with enzymes, genetic materials, and bio components within the cell. Pyrimidine derivatives have been used in a wide variety of pharmaceuticals including general anesthetics, anti-epilepsy medication, anti-malaria medication, drugs for treating high blood pressure, and HIV medication.SDS of cas: 16879-39-3
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia