Bioorganic & Medicinal Chemistry Letters | Cas: 18592-13-7 was involved in experiment

Saladino, Raffaele;Danti, Maria Chiara;Mincione, Enrico;Crestini, Claudia;Palamara, Anna Teresa;Savini, Patrizia;Marini, Stefano;Botta, Maurizio published 《A potent and selective inhibition of parainfluenza 1 (sendai) virus by new 6-oxiranyl-, 6-methyloxiranyluracils, and 4(3H)-pyrimidinone derivatives》. The research results were published in《Bioorganic & Medicinal Chemistry Letters》 in 1998.Name: 6-(Chloromethyl)pyrimidine-2,4(1H,3H)-dione The article conveys some information:

Several new 6-oxiranyl-, 6-methyloxiranyluracils, and pyrimidinone derivatives, I (R¹ = Me, Ph, CMe₃, R² = R³ = H; R¹ = R³ = Me, R² = H; R¹ = R² = Me, R³ = H; R¹R² = CH₂CH₂CH₂, CH₂CH₂CH₂CH₂, R³ = H), II (R⁴ = Me, H, R⁵ = Ph; R⁴ = Ph, R⁵ = H) and III (R¹R² = CH₂CH₂CH₂CH₂, R³ = H, R⁶ = CH₂CH₂Me; R¹ = Ph, R² = R³ = H, R⁶ = CH₂CH₂Me, cyclohexyl; R¹ = R³ = Me, R² = H, R⁶ = cyclohexyl), synthesized by the lithiation-alkylation sequence of 1,3,6-trimethyluracil (IV; R⁷ = Me), 1,3-dimethyl-6-chloromethyluracil(IV; R⁷ = CH₂Cl), and 2-alkoxy-6-methyl-4(3H)-pyrimidinones (V; R⁶ = Pr, cyclohexyl), resp., showed a potent and selective antiviral activity against the parainfluenza 1 (Sendai) virus replication. The experimental procedure involved many compounds, such as 6-(Chloromethyl)pyrimidine-2,4(1H,3H)-dione (cas: 18592-13-7) .

6-(Chloromethyl)pyrimidine-2,4(1H,3H)-dione (cas: 18592-13-7 Name: 6-(Chloromethyl)pyrimidine-2,4(1H,3H)-dione) was used in the synthesis of: 5-bromo-6-(chloromethyl)uracil, pteridine compounds, potential anticancer agents, substituted uracil pyridinium compounds, potential inhibitors of thymidine phosphorylase.

Reference:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia