The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 145783-14-8, name is 4,6-Dichloro-5-nitro-2-(propylthio)pyrimidine. This compound has unique chemical properties. The synthetic route is as follows. 145783-14-8
Example 3. Preparation of l-^SaR^S^R^aSV-ftS-Amino–chloro-l- phiropylthioJpyrimidin-^yllaminoJ-ljl-dimethyltetrahydro-SaH- cyclopenta[ 99%). The catalyst was filtered off and washed with methyl-tert-butylether (117 kg). The hydrogenation was repeated with a second portion of 4,6-Dichloro-5-nitro-2-(propylthio)pyrimidine (71 kg). The two hydrogenation solutions were combined. Water was separated off and the organic layer was distilled under reduced pressure and at a jacket temperature of 300C. To the resulting brown oil ethylene glycol (221 kg) was charged and the distillation was continued until no more methyl-tert-butylether was distilling off.
Statistics shows that 145783-14-8 is playing an increasingly important role. we look forward to future research findings about 4,6-Dichloro-5-nitro-2-(propylthio)pyrimidine.
Reference:
Patent; ASTRAZENECA AB; AUFDENBLATTEN, Rhony; BOHLIN, Martin, Hans; HELLSTROeM, Helena; JOHANSSON, Peter, W; LARSSON, Ulf, G; RECKNAGEL, Mikaela; WEISS, Ursula, heiress of WEISS Andreas (Deceased); WO2010/30224; (2010); A1;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia