Reference of 160199-05-3, Adding some certain compound to certain chemical reactions, such as: 160199-05-3, name is 2,4-Dichlorobenzo[4,5]thieno[3,2-d]pyrimidine,molecular formula is C10H4Cl2N2S, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 160199-05-3.
2,4-dichlorobenzo [4,5] thieno [3,2-d] pyrimidine (32 g, 125.6 mmol)(35 g, 138 mmol), 4,4,5,5-tetramethyl-2- (naphthalen-2-yl) -1,3,2-dioxaborolanePd (PPh3) 4 (5.80 g, 5.02 mmol),K2CO3 (52 g, 376.41 mmol), THF (440 mL),Water (220 ml) was added, and the temperature of the reaction product was increased to 80 C, followed by stirring for 6 hours. When the reaction is terminated, water is removed from the reaction,After filtration under reduced pressure, it was dried with MgSO4 and concentrated. The resulting compound was purified by silicagel column and recrystallized to obtain 19.58 g (yield: 45%) of the product.
According to the analysis of related databases, 160199-05-3, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Duksan Neolux Co.,Ltd.; Yoon Jin-ho; Jeong Ho-yeong; Park Mu-jin; Kim Jeong-seok; Lee Seon-hui; (46 pag.)KR2018/128292; (2018); A;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia