As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 4214-85-1, name is 2-Amino-6-methyl-5-nitro-3H-pyrimidin-4-one, molecular formula is C5H6N4O3, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below. COA of Formula: C5H6N4O3
A suspension of 2-amino-6-methyl-5-nitropyrimidin-4-one (G. N. Mitchell et. al. J. Org. Chem . , 1974, 39, 176) (20.0 g) in acetic anhydride (120 ML) was heated under reflux for 0.5 h.. The cooled suspension was filtered and the solids washed with ether to give 2-N-acetyl-6-methyl-5-nitropyrimidin-4-one (19.7 g).. 13C NMR (d6-DMSO) delta 174.5, 161.9, 153.3, 150.9, 133.8, 24.2, 21.4.
With the rapid development of chemical substances, we look forward to future research findings about 4214-85-1.
Reference:
Patent; Industrial Research Limited; Albert Einstein College of Medicine of Yesheva University; US6693193; (2004); B1;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia