The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 75833-38-4, name is 2-Chloropyrimidine-4-carbonitrile. This compound has unique chemical properties. The synthetic route is as follows. Computed Properties of C5H2ClN3
Reference Example 107 tert-Butyl [methyl(6-cyano-2-pyrimidinyl)amino]acetate 2-Chloro-6-cyanopyrimidine (1.45 g, 10.4 mmol), sarcosine tert-butyl ester hydrochloric acid (1.89 g, 10.4 mmol) and triethylamine (1.60 ml, 11.4 mmol) were added to DMF (30 ml), and the mixture was stirred at room temperature for 18 hrs.. The reaction mixture was combined with ethyl acetate and water.. The organic layer was washed with saturated brine and dried over anhydrous magnesium sulfate.. The solvent was evaporated to give the titled compound (1.99 g, 77 %) as pale yellow crystals.1H-NMR (CDCl3) delta: 1.47 (9H, s), 3.24 (3H, d, J = 5.5 Hz), 4.22 (2H, d, J = 8.7 Hz), 6.80 (1H, d, J = 4.7 Hz), 8.43-8.51 (1H, m). IR(-KBr): 2237, 1736, 1574, 1537, 1410, 1365, 1226, 1153, 1033, 815 cm-1.
With the rapid development of chemical substances, we look forward to future research findings about 75833-38-4.
Reference:
Patent; Takeda Chemical Industries, Ltd.; EP1424336; (2004); A1;,
Pyrimidine | C4H4N2 – PubChem,
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