2380-63-4, Adding a certain compound to certain chemical reactions, such as: 2380-63-4, 1H-Pyrazolo[3,4-d]pyrimidin-4-amine, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, 2380-63-4, blongs to pyrimidines compound.
IH-pyrazolo[3 4-dJpynmidn4arnine (1 5g 1111 mmol) was suspended in 15 nil of DMF and Nodosuccnmde (1 2 eq 3 0 g 13 34 mmol) added The mixture was heated at 180 0C in the microwave for an hour. EtOH (80 m) was added to the reacUonand a precipitate began to fo rn, hich was aided by sonicaton The preuipitate wasfiltered and Washed with EtOH (x3, 20 ml) and aUowed to dry in an oven at 40 Coveimghtto give a sand cooured soid (2115 g, 8105 mmol 730%) ?H NMR (500MHz, DMS06 13.80 (s, IN), 8.i(s, 1H) 7,796:.44 (m 2H);13C NMR (126 MHz,DM80) 6 157 60 (C) 156 08 CH) 155 04 (C), 102 50 (C), 89 82 (C) MS (ES +ve)[M+H)?: 283.9 (+Na), (ES -ye) [M-Hf: 259.9. 287.8 (+Na).
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,2380-63-4, its application will become more common.
Reference:
Patent; THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH; UNCITI-BROCETA, Asier; FRASER, Craig; O. CARRAGHER, Neil; (146 pag.)WO2016/185160; (2016); A1;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia