As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 5604-46-6, name is 2-Amino-4,6-dichloropyrimidine-5-carbaldehyde, molecular formula is C5H3Cl2N3O, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below. Recommanded Product: 5604-46-6
1 (324 mg, 1.7 mmol) was dissolved in a mixed solution of 7 mL of tetrahydrofuran and water (3:1), warmed to 50 C, and hydrazine hydrate (170 mg, 3.3 mmol) was dissolved in 1.7 mL of water, slowly dripping Adding to the reaction solution, stirring for 40 min, the reaction solution was poured into 8 mL of ice water and stirred for 15 min, allowed to stand for 20 min, then filtered, and the filter cake was washed with acetone to obtain 0.23 g of pale yellow solid, yield 78.4%
With the rapid development of chemical substances, we look forward to future research findings about 5604-46-6.
Reference:
Patent; China Pharmaceutical University; Lai Yisheng; Di Rongrong; Ma Jun; Wang Lei; Liu Yu; Gu Mengyue; Kang Nannan; Li Yuezhen; (15 pag.)CN108371662; (2018); A;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia