Synthesis and antimicrobial activity of pyrimidinylsulfamoyl azolylbenzamides was written by Butta, Ragavendra;Ummadi, Nagarjuna;Adivireddy, Padmaja;Venkatapuram, Padmavathi. And the article was included in Indian Journal of Chemistry in 2019.Recommanded Product: 4,6-Diphenylpyrimidin-2-amine This article mentions the following:
A variety of sulfonamide linked azolyl pyrimidines I [R = H, Cl, Br, Me, NO2; X = O, S, NH] were prepared and studied for their antimicrobial activity. The chloro and nitro substituted thiazolyl pyrimidines I [R = Cl, NO2; X = S] displayed potential antibacterial activity against Bacillus subtilis. The chloro, bromo and nitro substituted imidazolyl pyrimidines I [R = Cl, Br, NO2; X = NH] showed potential antifungal activity against A. niger. In the experiment, the researchers used many compounds, for example, 4,6-Diphenylpyrimidin-2-amine (cas: 40230-24-8Recommanded Product: 4,6-Diphenylpyrimidin-2-amine).
4,6-Diphenylpyrimidin-2-amine (cas: 40230-24-8) belongs to pyrimidine derivatives. Pyrimidines are isomeric with two other forms of diazines: pyridazine, with the nitrogen atoms in the 1 and 2 positions; and pyrazine, with the nitrogen atoms in the 1 and 4 positions. Therapy for fungal infections is based mainly on four classes of antifungals: azoles, echinocandins, polyenes, and pyrimidine analogs.Recommanded Product: 4,6-Diphenylpyrimidin-2-amine
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia